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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 16.97
Human Site: S936 Identified Species: 23.33
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S936 R K S Y L Y P S T L V R T E P
Chimpanzee Pan troglodytes XP_507923 1056 119132 S936 R K S Y L Y P S T L V R T E P
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 K745 E K C E N I Q K P L S S V Q E
Dog Lupus familis XP_534964 1334 149091 S1218 R K N Y L Y P S T L V R T E P
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 T935 R K K Y L Y P T T L V R T E P
Rat Rattus norvegicus O55165 796 89797 R688 T S A V G Y K R P I S Q Y A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 N991 N Q E L L Q E N D V L K Q K M
Frog Xenopus laevis P28025 1060 119314 S940 R R D Y A Y P S L L V K T K P
Zebra Danio Brachydanio rerio NP_775368 955 106984 I847 A Q E Q L K L I R Q T D T A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 R943 K R D F V Y P R T L V A T S P
Honey Bee Apis mellifera XP_623508 706 80766 I598 K C L N D C K I A F M N V S I
Nematode Worm Caenorhab. elegans P46873 699 78760 L591 M S M S R T I L P L A N N G Y
Sea Urchin Strong. purpuratus P46872 699 78679 D591 R L S M L I I D S F I P Q E F
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 K946 C E D L R Q L K G S H Y H K I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 E932 C C Q A R C I E D K A Q E T F
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 A991 P E A S V I K A L P L L D Y P
Red Bread Mold Neurospora crassa P48467 928 102392 R820 K E V A I A E R K L M A R N E
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 13.3 93.3 N.A. 86.6 6.6 N.A. N.A. 6.6 60 13.3 N.A. 46.6 0 6.6 26.6
P-Site Similarity: 100 100 20 100 N.A. 93.3 26.6 N.A. N.A. 46.6 80 20 N.A. 73.3 13.3 6.6 40
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 0 N.A. N.A. 0 6.6 6.6
P-Site Similarity: 13.3 N.A. N.A. 6.6 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 12 12 6 6 0 6 6 0 12 12 0 12 0 % A
% Cys: 12 12 6 0 0 12 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 18 0 6 0 0 6 12 0 0 6 6 0 0 % D
% Glu: 6 18 12 6 0 0 12 6 0 0 0 0 6 30 12 % E
% Phe: 0 0 0 6 0 0 0 0 0 12 0 0 0 0 12 % F
% Gly: 0 0 0 0 6 0 0 0 6 0 0 0 0 6 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 6 0 6 0 0 % H
% Ile: 0 0 0 0 6 18 18 12 0 6 6 0 0 0 12 % I
% Lys: 18 30 6 0 0 6 18 12 6 6 0 12 0 18 0 % K
% Leu: 0 6 6 12 42 0 12 6 12 53 12 6 0 0 0 % L
% Met: 6 0 6 6 0 0 0 0 0 0 12 0 0 0 6 % M
% Asn: 6 0 6 6 6 0 0 6 0 0 0 12 6 6 0 % N
% Pro: 6 0 0 0 0 0 36 0 18 6 0 6 0 0 42 % P
% Gln: 0 12 6 6 0 12 6 0 0 6 0 12 12 6 0 % Q
% Arg: 36 12 0 0 18 0 0 18 6 0 0 24 6 0 6 % R
% Ser: 0 12 18 12 0 0 0 24 6 6 12 6 0 12 0 % S
% Thr: 6 0 0 0 0 6 0 6 30 0 6 0 42 6 0 % T
% Val: 0 0 6 6 12 0 0 0 0 6 36 0 12 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 30 0 42 0 0 0 0 0 6 6 6 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _